Tasmania's border will reopen to South Australia at 12:01am Thursday.
It'll be classified as a low-risk jurisdiction, meaning arrivals won't have to quarantine - unless they've been in a specific hotspot identified by South Australian Health as connected to the recent coronavirus cluster in Adelaide.
Director of Public Health Mark Veitch is set to provide more detail on those places.
South Australia recorded no new COVID-19 cases on Tuesday.
11 of the 33 infections linked to the Parafield cluster are still active - while about 1,100 people are in quarantine.
Premier Peter Gutwein believes the border wall coming down is a sign our economy is springing back to life.
"This is a significant milestone and will mean for the first time in 9 months Madam Speakier, Tasmania's border will be relaxed with all states and territories as well as New Zealanders," he told parliament.
Tasmania reopened to Victoria last Friday.