A Sorell woman's in the Royal Hobart Hospital with serious head injuries after a crash on the Lyell Highway east of Queenstown.
The 53-year-old collided with a ute near Nelson Falls on Thursday afternoon and was airlifted from the scene.
The car's driver, a 24-year-old Howrah man, wasn't hurt.
Police are reiterating the road safety message after a Launceston man died in a similar smash near Hamilton recently, the state's first fatality of the year.
Image: Tasmania Police