UPDATE 10:30 am Thursday: Ms Goldsmith has been found safe.
There are concerns for the welfare of a woman who's vanished east of Hobart and the Westpac Rescue helicopter is assisting the search.
Amanda Goldsmith was last seen in the Cambridge area at 11 am on Wednesday.
Ms Goldsmith was at the Big 4 Airport Tourist Park wearing black pants and a long sleeve pink nightie.
The 53-year-old, who has brown shoulder-length hair, may be wearing a black puffer jacket with a fur-lined hood.
"Police, including the Westpac Rescue Helicopter, are currently searching the Cambridge area," said a police statement.
"Anyone who has seen Amanda or knows her current whereabouts is urged to contact police on 131 444."